- 1 182
- 3 145 275
Broad Institute
United States
Приєднався 24 лип 2010
A unique, collaborative community pioneering a new model of biomedical science.
LatinX@Broad Presents The René Salazar Speaker Series: Lucas Marinho (2024)
René Salazar Speaker Series
June 11, 2024
Broad Institute of MIT and Harvard
Dr. Lucas Marinho
E62 Bio: Providing Life-Science Solutions for Neglected Diseases and Underserved Communities
For more information visit: www.broadinstitute.org
Copyright Broad Institute, 2024. All rights reserved.
June 11, 2024
Broad Institute of MIT and Harvard
Dr. Lucas Marinho
E62 Bio: Providing Life-Science Solutions for Neglected Diseases and Underserved Communities
For more information visit: www.broadinstitute.org
Copyright Broad Institute, 2024. All rights reserved.
Переглядів: 42
Відео
MPG Primer: Sequencing and analysis of long-read whole genome data (2024)
Переглядів 488День тому
Medical and Population Genetics Primer June 13, 2024 Broad Institute of MIT and Harvard Kiran Garimella Broad Institute Sequencing and analysis of long-read whole genome data The Primer on Medical and Population Genetics is a series of informal weekly discussions of basic genetics topics that relate to human populations and diseases. Experts from across the Broad Institute community give in-dep...
EWSC: Deep learning models for genomes and beyond, Olga Troyanskaya
Переглядів 903День тому
EWSC-MIT EECS Joint Colloquium Series Presented by Eric and Wendy Schmidt Center May 6, 2024 Broad Institute of MIT and Harvard Olga Troyanskaya Deep learning models for genomes and beyond This colloquium is part of an ongoing series that is jointly hosted by the Eric and Wendy Schmidt Center at the Broad Institute and AI D within the Department of Electrical Engineering and Computer Science at...
MIA: Zitnik Lab, Multimodal protein language models for deciphering protein function
Переглядів 74214 днів тому
Models, Inference and Algorithms May 29, 2024 Broad Institute of MIT and Harvard Marinka Zitnik Assistant Professor of Biomedical Informatics, Harvard Medical School Owen Queen Research Associate, Harvard Medical School Yepeng Huang PhD Student, Harvard Medical School Understanding the relationship between a protein's amino acid sequence and its structure or function is a long-standing challeng...
MPG Primer: Genomic Privacy: Key Issues and Emerging Solutions (2024)
Переглядів 20021 день тому
Medical and Population Genetics Primer March 28, 2024 Broad Institute of MIT and Harvard Genomic Privacy: Key Issues and Emerging Solutions Hoon Cho Yale University For more information visit: www.broadinstitute.org Copyright Broad Institute, 2024. All rights reserved.
MPG Primer: Introduction to Terra/AnVIL (2024)
Переглядів 17121 день тому
Medical and Population Genetics Primer May 16, 2024 Broad Institute of MIT and Harvard Anton Kovalsky Data Sciences Platform, Broad Institute Introduction to Terra/AnVIL The Primer on Medical and Population Genetics is a series of informal weekly discussions of basic genetics topics that relate to human populations and diseases. Experts from across the Broad Institute community give in-depth in...
MPG Primer: Cellarium (2024)
Переглядів 25021 день тому
Medical and Population Genetics Primer June 6, 2024 Broad Institute of MIT and Harvard Mehrtash Babadi Broad Institute Cellarium The Primer on Medical and Population Genetics is a series of informal weekly discussions of basic genetics topics that relate to human populations and diseases. Experts from across the Broad Institute community give in-depth introductions to the basic principles of co...
MPG Primer: Introduction to Pharmacogenetics (2024)
Переглядів 42521 день тому
Medical and Population Genetics Primer May 30, 2024 Broad Institute of MIT and Harvard Josephine Li Massachusetts General Hospital Introduction to Pharmacogenetics The Primer on Medical and Population Genetics is a series of informal weekly discussions of basic genetics topics that relate to human populations and diseases. Experts from across the Broad Institute community give in-depth introduc...
MIA: Jun Cheng, Alpha Missense; Primer by Žiga Avsec
Переглядів 33121 день тому
Models, Inference and Algorithms Broad Institute of MIT and Harvard March 13, 2024 Meeting: Accurate proteome-wide missense variant effect prediction with Alpha Missense Jun Cheng Google DeepMind The vast majority of missense variants observed in the human genome are of unknown clinical significance. We present Alpha Missense, an adaptation of AlphaFold fine-tuned on human and primate variant p...
Broad@20 - Origin Stories: How Broad’s earliest days sparked two decades of innovation
Переглядів 39721 день тому
Origin Stories: How Broad’s earliest days sparked two decades of innovation This edited broadcast originally aired on June 5, 2024 from the Broad Institute auditorium in Cambridge, MA. This story-telling event features some of Broad’s longest-serving scientists and other team members whose pioneering work on the Human Genome Project, the International HapMap Project, and other efforts built the...
MIA: Jose Alquicira-Hernandez, Scalable single-cell models for eQTL mapping; Primer by Aparna Nathan
Переглядів 37221 день тому
Models, Inference and Algorithms April 10, 2024 Broad Institute of MIT and Harvard Meeting: Scalable single-cell models for robust cell-state-dependent eQTL mapping Jose Alquicira-Hernandez Raychaudhuri Lab, Division of Genetics/Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital. Department of Medicine, Harvard Medical School. Modelling cell state-dependent genetic associati...
Variant To Function Symposium: Michael Talkowski
Переглядів 228Місяць тому
Variant To Function Symposium: Michael Talkowski
Variant to Function Symposium: Soumya Raychaudhuri
Переглядів 318Місяць тому
Variant to Function Symposium: Soumya Raychaudhuri
Variant to Function Symposium: Opening Remarks and Discussion on the Future of Human Genetics
Переглядів 508Місяць тому
Variant to Function Symposium: Opening Remarks and Discussion on the Future of Human Genetics
Variant to Function Symposium: Tune Pers
Переглядів 297Місяць тому
Variant to Function Symposium March 14, 224 Broad Institute of MIT and Harvard “Variant-to-Function in Obesity Research: Challenges and Opportunities” Tune Pers, PhD, Novo Nordisk Foundation Center for Basic Metabolic Research, Associate Professor at the University of Copenhagen, Novo Nordisk Foundation Center for Genomic Mechanisms of Disease at the Broad Institute For more information visit: ...
Variant to Function Symposium: Viraat Goel
Переглядів 276Місяць тому
Variant to Function Symposium March 14, 2024 Broad Institute of MIT and Harvard “Linking structure to function in metabolic and blood disorders using Region Capture Micro-C” Viraat Goel, PhD Student, Biological Engineering at MIT, lab of Anders Sejr Hansen For more information visit: www.broadinstitute.org Copyright Broad Institute, 2024. All rights reserved.
Variant to Function Symposium: Jian Shu
Переглядів 496Місяць тому
Variant to Function Symposium March 14, 2024 Broad Institute of MIT and Harvard “Decoding Cell Fates through Single Cell Genomics, Imaging, and Machine Learning.” Jian Shu, PhD, Assistant Professor at MGH and Harvard Medical School, Associate Member at the Broad Institute For more information visit: www.broadinstitute.org Copyright Broad Institute, 2024. All rights reserved.
Variant to Function Symposium: Paola Arlotta
Переглядів 728Місяць тому
Variant to Function Symposium March 14, 2024 Broad Institute of MIT and Harvard “Human brain chimeroids as avatars to study interindividual variation in response to disease risk” Paola Arlotta, PhD, Institute Member, Departmental Chair and Golub Family Professor of Stem Cell and Regenerative Biology at Harvard University For more information visit: www.broadinstitute.org Copyright Broad Institu...
Broad Discovery Series: Moving from "hit-or-miss" toward a brighter future for psychiatric care
Переглядів 315Місяць тому
Broad Discovery Series: Moving from "hit-or-miss" toward a brighter future for psychiatric care
MPG Primer: Genomic Interpretation, seqr and Matchmaker Exchange (2024)
Переглядів 421Місяць тому
MPG Primer: Genomic Interpretation, seqr and Matchmaker Exchange (2024)
MPG Primer: Structural Variation in Human Genomes (2024)
Переглядів 902Місяць тому
MPG Primer: Structural Variation in Human Genomes (2024)
MIA: J. Salzman, SPLASH Ultraefficient statistics-first analysis of raw sequencing data; T. Baharav
Переглядів 9002 місяці тому
MIA: J. Salzman, SPLASH Ultraefficient statistics-first analysis of raw sequencing data; T. Baharav
MIA: Post Doc Talks; Phillip Schneider, Kai Cao, Bojan Karlas, Chenyu Wang, Sandeep Kambhampati
Переглядів 3472 місяці тому
MIA: Post Doc Talks; Phillip Schneider, Kai Cao, Bojan Karlas, Chenyu Wang, Sandeep Kambhampati
MPG Primer: Understand Single Cell ATAC-Seq Data Analysis (2024)
Переглядів 9782 місяці тому
MPG Primer: Understand Single Cell ATAC-Seq Data Analysis (2024)
LatinX@Broad Presents The René Salazar Speaker Series: Juan Alvarez-Dominguez
Переглядів 1572 місяці тому
LatinX@Broad Presents The René Salazar Speaker Series: Juan Alvarez-Dominguez
MIA: S. Gurev & N. Youssef, Unsupervised viral antibody escape prediction for future-proof vaccines
Переглядів 5072 місяці тому
MIA: S. Gurev & N. Youssef, Unsupervised viral antibody escape prediction for future-proof vaccines
MIA: Lucy Gao, Data thinning to avoid double dipping; Primer by Yiqun Chen
Переглядів 3802 місяці тому
MIA: Lucy Gao, Data thinning to avoid double dipping; Primer by Yiqun Chen
MPG Primer: A Practical guide to bulk RNA-seq, including guidelines for eQTL analysis (2024)
Переглядів 1 тис.2 місяці тому
MPG Primer: A Practical guide to bulk RNA-seq, including guidelines for eQTL analysis (2024)
EWSC: Machine Learning in the Optimization and Discovery Loop, Andreas Krause
Переглядів 962 місяці тому
EWSC: Machine Learning in the Optimization and Discovery Loop, Andreas Krause
Thank you Broad Institute. Greetings from Bimac Research Group and Bioengineering Graduate Students from Universidad del Cauca, Colombia.
As of 12/20/20, there are 5,481 protein superfamilies on CATH.
A very inspiring story from Sonia and Eric!
Oustanding Event! Congratulations.
Nothing like independent drug testers results being destroyed for corporate profit...
Thankyou for this presentation and your work done on muc1. I am an effected muc1 person and hope that a treatment will occur sooner that later.
Wonderful stuff!
Systematic surveys indicate that protein evolution is not determined exclusively by selection on protein structure and function, but is also affected by the genomic position of the encoding genes, their expression patterns, their position in biological networks and possibly their robustness to mistranslation.
I saw this exact comment on another website, the US National Library of Medicine National Institutes of Health. Did you originally come up with this "integrated view of protein evolution?"